Lilo-El and her husband Bar-El were astronuats that were sent from Krypton, but lost for many years. They arrives in Metropolis after the Bizzaro Invasion. She wanted to start New Krypton in Metropolis by removing the 'apes' (humans). Like almost all Kryptonians, Lilo was weak against Kryptonite, and was eventually so badly poisoned by it that she had to be sent to the Phantom Zone to survive.